guanine - meaning and definition. What is guanine
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What (who) is guanine - definition

CHEMICAL COMPOUND
Guanine nucleotides; Guanine analogue; Guanin (Fish); Guanine rich region; 2-amino-6-hydroxypurine; 2-aminohypoxanthine; Guanines

guanine         
['gw?:ni:n]
¦ noun Biochemistry a compound that occurs in guano and fish scales, and is one of the four constituent bases of DNA and RNA.
Guanine deaminase         
  • Xanthine synthesis from guanine
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
Guanase; EC 3.5.4.3; Guanine aminase; Guanine aminohydrolase; Cypin; GDA (gene)
Guanine deaminase also known as cypin, guanase, guanine aminase, GAH, and guanine aminohydrolase is an aminohydrolase enzyme which converts guanine to xanthine. Cypin is a major cytosolic protein that interacts with PSD-95.
Guanine nucleotide exchange factor         
  • GTP]]
  • Schematic of GEF activation of a GTPase
PROTEINS WHICH REMOVE GDP FROM GTPASES
Guanine Nucleotide Exchange Factor; Guanine exchange factors; Guanine nucleotide exchange factors; Guanosine nucleotide exchange factors; Guanine nucleotide exchange protein; GNEF; Guanine-nucleotide exchange factor; Guanine exchange factor; GDP exchange factor; Ephexin5
Guanine nucleotide exchange factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP). A variety of unrelated structural domains have been shown to exhibit guanine nucleotide exchange activity.

Wikipedia

Guanine

Guanine () (symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called guanosine.

With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. This unsaturated arrangement means the bicyclic molecule is planar.

Examples of use of guanine
1. Normal DNA consists of four bases _ adenine, cytosine, guanine and thymine (known as A,C,G,T) _ molecules that spell out the genetic code in pairs.
2. Each chromosome is made up of a molecule of DNA in the shape of a double helix which is composed of four chemical bases represented by the letters A (adenine), T (thymine), G (guanine) and C (cytosine). The arrangement, or sequence, of the letters determines the cell‘s genetic code.